RESUMO
SUMMARY: Traumatized bone tissue has the capacity to repair itself so that it eventually regains its almost original form, even in the case of artificially inserted implants. The process that stays at the base of the regeneration is represented by osteogenesis or remote osteogenesis. The major difference between the two types of bone formation is the location of the cement line, which is located on the surface of the implant for contact osteogenesis and on the surface of the bone defect for remote osteogenesis. The aim of the present study was to assess the contact osteogenesis in the case of inserted titanium screws in holes with diameters of 1.8 mm and 1 mm respectively. The obtained results show, in the case of the groove with 1.8 mm that the newly proliferated bone represents 73.85 % of the total area, while in the case of the groove with 1 mm in diameter the value of the newly proliferated bone is 26.15 %. In conclusion, the insertion of titanium screws by self-tapping into the hole smaller than the core of the screw is accompanied by bone proliferation by contact osteogenesis much more modest than in the case of insertion into the hole larger than the core of the screw.
El tejido óseo traumatizado tiene la capacidad de reparar en forma espontánea, de modo que eventualmente recupera su forma casi original, incluso en el caso de implantes insertados artificialmente. El proceso que queda en la base de la regeneración está representado por la osteogénesis u osteogénesis a distancia. La principal diferencia entre los dos tipos de formación ósea es la ubicación de la línea de cemento, que se encuentra en la superficie del implante para la osteogénesis de contacto y en la superficie del defecto óseo para la osteogénesis remota. El objetivo del presente estudio fue evaluar la osteogénesis de contacto en el caso de tornillos de titanio insertados en forámenes con diámetros de 1,8 mm y 1 mm respectivamente. Los resultados obtenidos muestran, en el caso del surco de 1,8 mm que el hueso neoproliferado representa el 73,85 % del área total, mientras que en el caso del surco de 1 mm de diámetro el valor del hueso neoproliferado es del 26,15 %. En conclusión, la inserción de tornillos de titanio por autorroscantes en el foramen menor que el núcleo del tornillo se acompaña de una proliferación ósea por osteogénesis de contacto mucho más modesta que en el caso de la inserción en el foramen mayor que el núcleo del tornillo.
Assuntos
Animais , Masculino , Coelhos , Osteogênese , Próteses e Implantes , Titânio/química , Parafusos Ósseos , OsseointegraçãoAssuntos
Adenocarcinoma/diagnóstico , Carcinoma Papilar/diagnóstico , Linfoma não Hodgkin/diagnóstico , Neoplasias da Glândula Tireoide/diagnóstico , Adenocarcinoma/terapia , Adolescente , Carcinoma Papilar/terapia , Criança , Terapia Combinada , Feminino , Humanos , Radioisótopos do Iodo , Linfoma não Hodgkin/terapia , Masculino , Metástase Neoplásica , Cuidados Pós-Operatórios , Cintilografia , Glândula Tireoide/diagnóstico por imagem , Neoplasias da Glândula Tireoide/terapia , Tireoidectomia , Ultrassonografia , Contagem Corporal TotalRESUMO
Two procedures for isolation of lactoferrin are described using ion exchange and immunoaffinity chromatography. Electrophoretic mobility, molecular mass, isoelectric point and other physico-chemical properties of the antigen were studied. Immunodiffusion and immunoperoxidase techniques exhibited presence of the antigen in some tissues containing glandular epithelium as well as a decrease in lactoferrin content in malignization.
Assuntos
Lactoferrina/isolamento & purificação , Lactoglobulinas/isolamento & purificação , Leite Humano/análise , Neoplasias/análise , Cromatografia de Afinidade , Feminino , Humanos , Focalização Isoelétrica , Lactoferrina/análise , Distribuição TecidualAssuntos
Hipertireoidismo/radioterapia , Isótopos de Iodo/uso terapêutico , Formação de Anticorpos/efeitos da radiação , Autoanticorpos/imunologia , Humanos , Hipersensibilidade Tardia/imunologia , Hipertireoidismo/imunologia , Imunidade Celular/efeitos da radiação , Ativação Linfocitária/efeitos da radiação , TireoidectomiaRESUMO
Histostructural peculiarities of the toxic goiter tissue were compared with humoral parameters of the autoimmune aggression and with the lymphoblasttransformation intensity in 29 patients operated on for thyrotoxicosis. The intensity of intradermal hypersensitivity reaction of delayed type in response to homologous and autologous tissue of the toxic goiter was also investigated. The majority of the patients displayed marked signs of autoimmune aggression, regardless of the structure of the goiter parenchyma and the intensity of ilt lymphoid infiltration. Immunological disturbances increase with the rise in the clinical severity of thyrotoxicosis. It is suggested that immunological changes of toxic goiter have phasic development. Humoral manifestation of autoimmune aggression were marked and stable, whereas changes of cellular immunity were less significant and specific; they were apparently due to a secondary increase in the lymphocytic immunological activity.
Assuntos
Doença de Graves/imunologia , Formação de Anticorpos , Doenças Autoimunes/imunologia , Doença de Graves/patologia , Técnica de Placa Hemolítica , Humanos , Hipersensibilidade Tardia/imunologia , Hipersensibilidade Imediata/imunologia , Hipertireoidismo/imunologia , Imunidade Celular , Ativação Linfocitária , Glândula Tireoide/patologiaAssuntos
Doenças da Hipófise/imunologia , Rinite Alérgica Sazonal/imunologia , Alérgenos , Poeira , Humanos , Imunoglobulinas/análise , Síndromes de Imunodeficiência/complicações , Muco/imunologia , Mucosa Nasal/metabolismo , Doenças da Hipófise/etiologia , Hipersensibilidade Respiratória/complicações , Rinite/imunologia , Dióxido de SilícioRESUMO
Antibodies against rat myocardium were studied by means of histoimmunfluorescence (indirect technique) in 32 rheumatic fever patients. Antibodies were found in 54% of the cases without carditis or active rheumatic valvulitis and in 83% of those with carditis. The fluorescent patterns observed were : sarcolemmal, sarcoplasmic (intermyofibrillar) and smooth muscle of vessels. The sarcolemmal pattern was more frequently observed in rheumatic carditis while the intermyofibrillar one was more common in rheumatic fever without evidence of carditis as well as rheumatic valvulitis. The serum factors involved in the sarcolemmal fluorescence were inhibitied by the insoluble saline myocardium extract.